In the pharmaceutical industry, drug quality is related to life and health, which imposes extremely high requirements on the precision, stability and hygiene standards of production processes. Relying on its unique advantages, the inclined mixing granulator has become a key piece of equipment trusted by many pharmaceutical enterprises. Here are some practical application cases.
Case 1: Improving the Quality of Tablet Granules and Helping Pharmaceutical Enterprises Optimize Products
A well-known pharmaceutical enterprise faced the problem of unstable granule quality when producing a best-selling tablet drug. The uneven mixing of traditional granulation equipment led to large fluctuations in the disintegration time of tablets, affecting the efficacy of the drug. After introducing the inclined mixing granulator, the situation was greatly improved. Its inclined structure, combined with multi-dimensional stirring, enables materials to form complex convection during the mixing process, increasing the mixing uniformity from the original 80% to over 98%. The produced granules have uniform particle size and good fluidity. The compressed tablets not only have a stable disintegration time within the standard range, but also the quality consistency between batches of drugs has been significantly improved, which has significantly enhanced the market competitiveness of the products.
A well-known pharmaceutical enterprise faced the problem of unstable granule quality when producing a best-selling tablet drug. The uneven mixing of traditional granulation equipment led to large fluctuations in the disintegration time of tablets, affecting the efficacy of the drug. After introducing the inclined mixing granulator, the situation was greatly improved. Its inclined structure, combined with multi-dimensional stirring, enables materials to form complex convection during the mixing process, increasing the mixing uniformity from the original 80% to over 98%. The produced granules have uniform particle size and good fluidity. The compressed tablets not only have a stable disintegration time within the standard range, but also the quality consistency between batches of drugs has been significantly improved, which has significantly enhanced the market competitiveness of the products.
Case 2: Meeting the Requirements of Capsule Filling and Complying with Strict GMP Standards
Another pharmaceutical enterprise specializing in capsule preparation production has almost harsh requirements on the shape, density and purity of granules, and must strictly follow GMP specifications. The integrated design of the inclined mixing granulator completes the mixing and granulation processes in the same closed environment, reducing the risk of contamination caused by material transfer. At the same time, by precisely controlling parameters such as stirring speed and granulation pressure, granules with regular shape and moderate density can be produced, which perfectly adapts to the capsule filling process. The interior of the equipment is smooth without dead corners, easy to clean, and can easily pass GMP certification inspections, helping pharmaceutical enterprises achieve efficient and compliant production and reduce operational risks.
Another pharmaceutical enterprise specializing in capsule preparation production has almost harsh requirements on the shape, density and purity of granules, and must strictly follow GMP specifications. The integrated design of the inclined mixing granulator completes the mixing and granulation processes in the same closed environment, reducing the risk of contamination caused by material transfer. At the same time, by precisely controlling parameters such as stirring speed and granulation pressure, granules with regular shape and moderate density can be produced, which perfectly adapts to the capsule filling process. The interior of the equipment is smooth without dead corners, easy to clean, and can easily pass GMP certification inspections, helping pharmaceutical enterprises achieve efficient and compliant production and reduce operational risks.
Case 3: Reducing Production Costs and Improving Production Efficiency
A medium-sized pharmaceutical enterprise has long been troubled by the high-cost and low-efficiency production mode. The traditional granulation process is carried out step by step, with large equipment floor space, high energy consumption, and cumbersome manual operations that are prone to errors. After adopting the inclined mixing granulator, mixing and granulation are completed simultaneously, shortening the production cycle by 40% and saving a lot of labor and time costs. The intelligent control system of the equipment automatically adjusts the operating parameters according to the material properties, reducing energy consumption by more than 25%. In addition, due to its excellent mixing and granulation effect, the defective rate has dropped from 15% to less than 5%, reducing raw material waste. The comprehensive production cost has been significantly reduced, freeing up more profit space for the enterprise.
A medium-sized pharmaceutical enterprise has long been troubled by the high-cost and low-efficiency production mode. The traditional granulation process is carried out step by step, with large equipment floor space, high energy consumption, and cumbersome manual operations that are prone to errors. After adopting the inclined mixing granulator, mixing and granulation are completed simultaneously, shortening the production cycle by 40% and saving a lot of labor and time costs. The intelligent control system of the equipment automatically adjusts the operating parameters according to the material properties, reducing energy consumption by more than 25%. In addition, due to its excellent mixing and granulation effect, the defective rate has dropped from 15% to less than 5%, reducing raw material waste. The comprehensive production cost has been significantly reduced, freeing up more profit space for the enterprise.
From improving product quality, meeting regulatory standards to reducing costs and increasing efficiency, the inclined mixing granulator has achieved remarkable results in the pharmaceutical industry. It effectively solves the pain points of pharmaceutical enterprises and promotes the industry to a higher level of production quality.
